Construction and expression of the complete Clostridium difficile toxin A gene in Escherichia coli.
Cloned fragments constituting the 8.1-kb toxin A gene of Clostridium difficile were used to reconstruct the intact gene. The recombinant toxin expressed in Escherichia coli was cytotoxic, enterotoxic, and lethal. In addition, toxic lysate caused hemagglutination of rabbit erythrocytes. The toxic act...
Gorde:
| Argitaratua izan da: | Infect Immun |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Microbiology (ASM)
1991
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1987027/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.1.150-153.1991 |
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