Construction and expression of the complete Clostridium difficile toxin A gene in Escherichia coli.
Cloned fragments constituting the 8.1-kb toxin A gene of Clostridium difficile were used to reconstruct the intact gene. The recombinant toxin expressed in Escherichia coli was cytotoxic, enterotoxic, and lethal. In addition, toxic lysate caused hemagglutination of rabbit erythrocytes. The toxic act...
保存先:
| 出版年: | Infect Immun |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1991
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1987027/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.1.150-153.1991 |
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