Construction and expression of the complete Clostridium difficile toxin A gene in Escherichia coli.
Cloned fragments constituting the 8.1-kb toxin A gene of Clostridium difficile were used to reconstruct the intact gene. The recombinant toxin expressed in Escherichia coli was cytotoxic, enterotoxic, and lethal. In addition, toxic lysate caused hemagglutination of rabbit erythrocytes. The toxic act...
Kaydedildi:
| Yayımlandı: | Infect Immun |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1991
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1987027/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.1.150-153.1991 |
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