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Adult-Like Anti-Mycobacterial T Cell and In Vivo Dendritic Cell Responses Following Neonatal Immunization with Ag85B-ESAT-6 in the IC31® Adjuvant

BACKGROUND: With the exception of some live vaccines, e.g. BCG, subunit vaccines formulated with “classical” adjuvants do not induce similar responses in neonates as in adults. The usual neonatal profile is characterized by lower levels of TH1-associated biomarkers. This has hampered the development...

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Detalhes bibliográficos
Main Authors: Kamath, Arun T., Rochat, Anne-Françoise, Valenti, Mario P., Agger, Else Marie, Lingnau, Karen, Andersen, Peter, Lambert, Paul-Henri, Siegrist, Claire-Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577009/
https://ncbi.nlm.nih.gov/pubmed/18997860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003683
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