Immunological Memory Transferred with CD4 T Cells Specific for Tuberculosis Antigens Ag85B-TB10.4: Persisting Antigen Enhances Protection

BACKGROUND: High levels of death and morbidity worldwide caused by tuberculosis has stimulated efforts to develop a new vaccine to replace BCG. A number of Mycobacterium tuberculosis (Mtb)-specific antigens have been synthesised as recombinant subunit vaccines for clinical evaluation. Recently a fus...

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Hlavní autoři: Duffy, Darragh, Dawoodji, Amina, Agger, Else Marie, Andersen, Peter, Westermann, Jürgen, Bell, Eric B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788218/
https://ncbi.nlm.nih.gov/pubmed/20011592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008272
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