Expression and Immunogenicity of the Mycobacterial Ag85B/ESAT-6 Antigens Produced in Transgenic Plants by Elastin-Like Peptide Fusion Strategy

This study explored a novel system combining plant-based production and the elastin-like peptide (ELP) fusion strategy to produce vaccinal antigens against tuberculosis. Transgenic tobacco plants expressing the mycobacterial antigens Ag85B and ESAT-6 fused to ELP (TBAg-ELP) were generated. Purified...

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Detalhes bibliográficos
Main Authors: Floss, Doreen Manuela, Mockey, Michael, Zanello, Galliano, Brosson, Damien, Diogon, Marie, Frutos, Roger, Bruel, Timothée, Rodrigues, Valérie, Garzon, Edwin, Chevaleyre, Claire, Berri, Mustapha, Salmon, Henri, Conrad, Udo, Dedieu, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855997/
https://ncbi.nlm.nih.gov/pubmed/20414351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/274346
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