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Post-transcriptional Control of CCAAT/Enhancer-binding Protein β (C/EBPβ) Expression: FORMATION OF A NUCLEAR HuR-C/EBPβ mRNA COMPLEX DETERMINES THE AMOUNT OF MESSAGE REACHING THE CYTOSOL
In 3T3-L1 cells, HuR is constitutively expressed and prior to induction of differentiation localized predominantly to the nucleus. Within minutes of induction of differentiation, nuclear HuR binds to its target ligand mRNAs, and the complexes appear to move to the cytosol. One ligand mRNA is the CCA...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2576548/ https://ncbi.nlm.nih.gov/pubmed/18678862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805659200 |
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