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HuR binds to a single site on the C/EBPβ mRNA of 3T3-L1 Adipocytes

HuR is a ligand for nuclear mRNAs containing adenylate-uridylate rich elements in the 3′-untranslated region. Once bound to the mRNA, HuR is recognized by adapter proteins which then facilitate nuclear export of the complex. In the cytosol HuR is thought to function to control stability and translat...

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Hlavní autoři: Jones, Heath, Carver, Melinda, Pekala, Phillip H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839008/
https://ncbi.nlm.nih.gov/pubmed/17288991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.01.136
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