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HuR binds to a single site on the C/EBPβ mRNA of 3T3-L1 Adipocytes

HuR is a ligand for nuclear mRNAs containing adenylate-uridylate rich elements in the 3′-untranslated region. Once bound to the mRNA, HuR is recognized by adapter proteins which then facilitate nuclear export of the complex. In the cytosol HuR is thought to function to control stability and translat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jones, Heath, Carver, Melinda, Pekala, Phillip H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839008/
https://ncbi.nlm.nih.gov/pubmed/17288991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.01.136
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