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Calmodulin Mediates Differential Sensitivity of CaMKII and Calcineurin to Local Ca(2+) in Cardiac Myocytes
Calmodulin (CaM) mediates Ca-dependent regulation of numerous pathways in the heart, including CaM-dependent kinase (CaMKII) and calcineurin (CaN), yet the local Ca(2+) signals responsible for their selective activation are unclear. To assess when and where CaM, CaMKII, and CaN may be activated in t...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2576378/ https://ncbi.nlm.nih.gov/pubmed/18689454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.128728 |
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