Involvement of Type 4 cAMP-Phosphodiesterase in the Myogenic Differentiation of L6 Cells

Myogenic cell differentiation is induced by Arg(8)-vasopressin, whereas high cAMP levels and protein kinase A (PKA) activity inhibit myogenesis. We investigated the role of type 4 phosphodiesterase (PDE4) during L6-C5 myoblast differentiation. Selective PDE4 inhibition resulted in suppression of dif...

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Detalhes bibliográficos
Main Authors: Naro, Fabio, Sette, Claudio, Vicini, Elena, De Arcangelis, Vania, Grange, Muriel, Conti, Marco, Lagarde, Michel, Molinaro, Mario, Adamo, Sergio, Némoz, Georges
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25763/
https://ncbi.nlm.nih.gov/pubmed/10588663
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