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The mRNA encoding a high-affinity cAMP phosphodiesterase is regulated by hormones and cAMP.

To elucidate the mechanisms by which hormones regulate cAMP phosphodiesterases (PDEs), a group of cDNA clones that had been isolated from a rat Sertoli cell library were characterized. These cDNAs are derived from a single gene (ratPDE3). The deduced amino acid sequence of the ratPDE3 cDNA correspon...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Swinnen, J V, Joseph, D R, Conti, M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298247/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554303/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8197
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