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Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae.

Saccharomyces cerevisiae strains expressing the activated RAS2Val19 gene or lacking both cAMP phosphodiesterase genes, PDE1 and PDE2, have impaired growth control and display an acute sensitivity to heat shock. We have isolated two classes of mammalian cDNAs from yeast expression libraries that supp...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Colicelli, J, Nicolette, C, Birchmeier, C, Rodgers, L, Riggs, M, Wigler, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51350/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1849280/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.7.2913
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