Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product.

Protein prenylation occurs by modification of proteins with one of at least two isoprenoids, the farnesyl group and the geranylgeranyl group. Protein farnesyltransferases have been identified, but no such enzyme has been identified for geranylgeranylation. We report the identification of an activity...

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Bibliografiske detaljer
Main Authors: Finegold, A A, Johnson, D I, Farnsworth, C C, Gelb, M H, Judd, S R, Glomset, J A, Tamanoi, F
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC51677/
https://ncbi.nlm.nih.gov/pubmed/2034682
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