The mRNA encoding a high-affinity cAMP phosphodiesterase is regulated by hormones and cAMP.
To elucidate the mechanisms by which hormones regulate cAMP phosphodiesterases (PDEs), a group of cDNA clones that had been isolated from a rat Sertoli cell library were characterized. These cDNAs are derived from a single gene (ratPDE3). The deduced amino acid sequence of the ratPDE3 cDNA correspon...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1989
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8197 |
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