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Involvement of Type 4 cAMP-Phosphodiesterase in the Myogenic Differentiation of L6 Cells

Myogenic cell differentiation is induced by Arg(8)-vasopressin, whereas high cAMP levels and protein kinase A (PKA) activity inhibit myogenesis. We investigated the role of type 4 phosphodiesterase (PDE4) during L6-C5 myoblast differentiation. Selective PDE4 inhibition resulted in suppression of dif...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: Naro, Fabio, Sette, Claudio, Vicini, Elena, De Arcangelis, Vania, Grange, Muriel, Conti, Marco, Lagarde, Michel, Molinaro, Mario, Adamo, Sergio, Némoz, Georges
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10588663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.10.12.4355
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