AKT KINASE REDUCING ENDOPLASMIC RETICULUM Ca(2+) RELEASE PROTECTS CELLS FROM Ca(2+)-DEPENDENT APOPTOTIC STIMULI

The proto-oncogene AKT is a potent inhibitor of apoptosis, and it is activated in many human cancers. A number of recent studies have highlighted the importance of the inositol 1,4,5-trisphosphate (IP3) receptor (IP3R) in mediating calcium (Ca(2+)) transfer from the Endoplasmic Reticulum (ER) to the...

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Main Authors: Marchi, Saverio, Rimessi, Alessandro, Giorgi, Carlotta, Baldini, Claudio, Ferroni, Letizia, Rizzuto, Rosario, Pinton, Paolo
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576286/
https://ncbi.nlm.nih.gov/pubmed/18723000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.07.153
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