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Mitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer Therapy

Autophagy is a tightly regulated catabolic pathway that terminates in the lysosomal compartment after the formation of a cytoplasmic vacuole that engulfs macromolecules and organelles. Notably, autophagy is associated with several human pathophysiological conditions, playing either a cytoprotective...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Patergnani, Simone, Missiroli, Sonia, Marchi, Saverio, Giorgi, Carlotta
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515599/
https://ncbi.nlm.nih.gov/pubmed/26284195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00173
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