Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 Mutants

The p53 protein is probably the most important tumor suppressor, acting as a nuclear transcription factor primarily through the modulation of cell death. However, currently, it is well accepted that p53 can also exert important transcription-independent pro-cell death actions. Indeed, cytosolic loca...

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Библиографические подробности
Опубликовано в: :Front Oncol
Главные авторы: Giorgi, Carlotta, Bonora, Massimo, Missiroli, Sonia, Morganti, Claudia, Morciano, Giampaolo, Wieckowski, Mariusz R., Pinton, Paolo
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2016
Предметы:
Oncology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766755/
https://ncbi.nlm.nih.gov/pubmed/26942128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00042
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