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p53 at the endoplasmic reticulum regulates apoptosis in a Ca(2+)-dependent manner
The tumor suppressor p53 is a key protein in preventing cell transformation and tumor progression. Activated by a variety of stimuli, p53 regulates cell-cycle arrest and apoptosis. Along with its well-documented transcriptional control over cell-death programs within the nucleus, p53 exerts crucial...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4330769/ https://ncbi.nlm.nih.gov/pubmed/25624484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410723112 |
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