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AKT KINASE REDUCING ENDOPLASMIC RETICULUM Ca(2+) RELEASE PROTECTS CELLS FROM Ca(2+)-DEPENDENT APOPTOTIC STIMULI
The proto-oncogene AKT is a potent inhibitor of apoptosis, and it is activated in many human cancers. A number of recent studies have highlighted the importance of the inositol 1,4,5-trisphosphate (IP3) receptor (IP3R) in mediating calcium (Ca(2+)) transfer from the Endoplasmic Reticulum (ER) to the...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2576286/ https://ncbi.nlm.nih.gov/pubmed/18723000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.07.153 |
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