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Regulation of the epithelial Na(+) channel by endothelin-1 in rat collecting duct
We used patch-clamp electrophysiology to investigate regulation of the epithelial Na(+) channel (ENaC) by endothelin-1 (ET-1) in isolated, split-open rat collecting ducts. ET-1 significantly decreases ENaC open probability by about threefold within 5 min. ET-1 decreases ENaC activity through basolat...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2576140/ https://ncbi.nlm.nih.gov/pubmed/18667482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90321.2008 |
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