Cellular pertussis vaccine containing a Bordetella pertussis strain that produces a nontoxic pertussis toxin molecule.

Bordetella pertussis 165-9K/129G, which produces a nontoxic form of pertussis toxin (PT), was used to prepare a whole-cell diphtheria-tetanus-pertussis (DTP) vaccine. The in vivo potency and the serological response induced by this vaccine were comparable to those of the conventional DTP vaccine whi...

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Publié dans:	Infect Immun
Auteurs principaux:	Marsili, I, Pizza, M, Giovannoni, F, Volpini, G, Bartalini, M, Olivieri, R, Rappuoli, R, Nencioni, L
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1541530/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.3.1150-1155.1992
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