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Cellular pertussis vaccine containing a Bordetella pertussis strain that produces a nontoxic pertussis toxin molecule.

Bordetella pertussis 165-9K/129G, which produces a nontoxic form of pertussis toxin (PT), was used to prepare a whole-cell diphtheria-tetanus-pertussis (DTP) vaccine. The in vivo potency and the serological response induced by this vaccine were comparable to those of the conventional DTP vaccine whi...

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Bibliografiske detaljer
Main Authors: Marsili, I, Pizza, M, Giovannoni, F, Volpini, G, Bartalini, M, Olivieri, R, Rappuoli, R, Nencioni, L
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC257606/
https://ncbi.nlm.nih.gov/pubmed/1541530
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