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Properties of pertussis toxin mutant PT-9K/129G after formaldehyde treatment.

Formaldehyde treatment is a method routinely used to detoxify diphtheria, tetanus, and pertussis toxins as well as other molecules suitable for vaccine production. To investigate whether chemical detoxification alters the immunological properties of vaccine components, we have treated the pertussis...

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Autors principals: Nencioni, L, Volpini, G, Peppoloni, S, Bugnoli, M, De Magistris, T, Marsili, I, Rappuoli, R
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC257803/
https://ncbi.nlm.nih.gov/pubmed/1702767
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