Subunit S1 of pertussis toxin: mapping of the regions essential for ADP-ribosyltransferase activity.

The toxicity of pertussis toxin is mediated by the ADP-ribosyltransferase activity of subunit S1. To understand the structure-function relationship of subunit S1 and guide the construction of nontoxic molecules suitable for vaccines, we constructed and expressed in Escherichia coli a series of amino...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Pizza, M, Bartoloni, A, Prugnola, A, Silvestri, S, Rappuoli, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2902632/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.20.7521
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