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Subunit S1 of pertussis toxin: mapping of the regions essential for ADP-ribosyltransferase activity.

The toxicity of pertussis toxin is mediated by the ADP-ribosyltransferase activity of subunit S1. To understand the structure-function relationship of subunit S1 and guide the construction of nontoxic molecules suitable for vaccines, we constructed and expressed in Escherichia coli a series of amino...

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Bibliografische gegevens
Hoofdauteurs: Pizza, M, Bartoloni, A, Prugnola, A, Silvestri, S, Rappuoli, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1988
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC282223/
https://ncbi.nlm.nih.gov/pubmed/2902632
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