Subunit S1 of pertussis toxin: mapping of the regions essential for ADP-ribosyltransferase activity.
The toxicity of pertussis toxin is mediated by the ADP-ribosyltransferase activity of subunit S1. To understand the structure-function relationship of subunit S1 and guide the construction of nontoxic molecules suitable for vaccines, we constructed and expressed in Escherichia coli a series of amino...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1988
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2902632/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.20.7521 |
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