Corticosteroids induce COX-2 expression in cardiomyocytes: role of glucocorticoid receptor and C/EBP-β

Psychological stress increases the level of glucocorticoids in the circulating system. We found that dexamethasone administration in adult mice elevates the expression of COX-2 in the myocardium. With isolated neonatal cardiomyocytes, corticosterone (CT) at physiologically relevant doses (0.01–1 μM)...

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Bibliographic Details
Main Authors: Sun, Haipeng, Sheveleva, Elena, Xu, Beibei, Inoue, Hiroyasu, Bowden, Tim G., Chen, Qin M.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2008
Subjects:
Muscle Cell Biology and Cell Motility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575824/
https://ncbi.nlm.nih.gov/pubmed/18650268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.90646.2007
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