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Do Amyloid Oligomers Act As Traps for Misfolded Proteins? A Hypothesis

Mounting evidence points to soluble peptide oligomers as the primary agents in various amyloid and prion diseases. Multiple mechanisms appear to contribute to the cytotoxic effects of these oligomers. Here, an additional, general mechanism is proposed. Hypothesis: soluble amyloid peptide oligomers s...

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Autor principal: Gruschus, James M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575656/
https://ncbi.nlm.nih.gov/pubmed/18925454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13506120802193746
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