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Do Amyloid Oligomers Act As Traps for Misfolded Proteins? A Hypothesis

Mounting evidence points to soluble peptide oligomers as the primary agents in various amyloid and prion diseases. Multiple mechanisms appear to contribute to the cytotoxic effects of these oligomers. Here, an additional, general mechanism is proposed. Hypothesis: soluble amyloid peptide oligomers s...

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Detalhes bibliográficos
Autor principal: Gruschus, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575656/
https://ncbi.nlm.nih.gov/pubmed/18925454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13506120802193746
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