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Do Amyloid Oligomers Act As Traps for Misfolded Proteins? A Hypothesis
Mounting evidence points to soluble peptide oligomers as the primary agents in various amyloid and prion diseases. Multiple mechanisms appear to contribute to the cytotoxic effects of these oligomers. Here, an additional, general mechanism is proposed. Hypothesis: soluble amyloid peptide oligomers s...
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2008
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575656/ https://ncbi.nlm.nih.gov/pubmed/18925454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13506120802193746 |
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