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uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo

Meningioma is a well-known tumor of the central nervous system, and is treated by surgical resection and/or radiation. Recently, ionizing radiation has been shown to enhance invasiveness of surviving tumor cells, and several proteolytic enzyme molecules, including urokinase plasminogen activator (uP...

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Detalhes bibliográficos
Main Authors: Kargiotis, Odysseas, Chetty, Chandramu, Gogineni, Venkateswara, Gondi, Christopher S., Pulukuri, Sai MuraliKrishna, Kyritsis, Athanassios P., Gujrati, Meena, Dinh, Dzung H., Rao, Jasti S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575644/
https://ncbi.nlm.nih.gov/pubmed/18949356
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