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RNAi-mediated Downregulation of Radiation-induced MMP-9 Leads to Apoptosis via Activation of ERK and Akt in IOMM-Lee cells

Patients afflicted with meningiomas are most often treated with radiation therapy followed by surgical resection. However, resistance to radiation treatment has been well documented among different cancers of the brain. In this study, we demonstrate that the malignant meningioma cells (IOMM-Lee cell...

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Autors principals: Gogineni, Venkateswara Rao, Kargiotis, Odysseas, Klopfenstein, Jeff, Gujrati, Meena, Dinh, Dzung H., Rao, Jasti S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605673/
https://ncbi.nlm.nih.gov/pubmed/19082492
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