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Enhancing Cardiovascular Dynamics by Inhibition of Thrombospondin-1/CD47 Signaling

Activation of soluble guanylate cyclase by nitric oxide (NO) controls signaling pathways that play critical roles in normal vascular physiology and in the pathogenesis of cardiovascular disease. We have identified the secreted protein thrombospondin-1 as a key regulator of NO signaling. Thrombospond...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Isenberg, Jeff S., Frazier, William A., Krishna, Murali C., Wink, David A., Roberts, David D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575641/
https://ncbi.nlm.nih.gov/pubmed/18855617
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