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Enhancing Cardiovascular Dynamics by Inhibition of Thrombospondin-1/CD47 Signaling

Activation of soluble guanylate cyclase by nitric oxide (NO) controls signaling pathways that play critical roles in normal vascular physiology and in the pathogenesis of cardiovascular disease. We have identified the secreted protein thrombospondin-1 as a key regulator of NO signaling. Thrombospond...

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Hlavní autoři: Isenberg, Jeff S., Frazier, William A., Krishna, Murali C., Wink, David A., Roberts, David D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575641/
https://ncbi.nlm.nih.gov/pubmed/18855617
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