Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction

The caspase recruitment domain (CARD) of intracellular adaptors and sensors plays a critical role in the assembly of signaling complexes involved in innate host defense against pathogens and in the regulation of inflammatory responses. The cytosolic receptor retinoic acid-inducible gene-I (RIG-I) re...

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Autori principali: Gack, Michaela U., Kirchhofer, Axel, Shin, Young C., Inn, Kyung-Soo, Liang, Chengyu, Cui, Sheng, Myong, Sua, Ha, Taekjip, Hopfner, Karl-Peter, Jung, Jae U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575490/
https://ncbi.nlm.nih.gov/pubmed/18948594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804947105
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