Insights into the structural dynamics of the Hsp110–Hsp70 interaction reveal the mechanism for nucleotide exchange activity

Hsp110 proteins are relatives of canonical Hsp70 chaperones and are expressed abundantly in the eukaryotic cytosol. Recently, it has become clear that Hsp110 proteins are essential nucleotide exchange factors (NEFs) for Hsp70 chaperones. Here, we report the architecture of the complex between the ye...

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Detaylı Bibliyografya
Asıl Yazarlar: Andréasson, Claes, Fiaux, Jocelyne, Rampelt, Heike, Druffel-Augustin, Silke, Bukau, Bernd
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575452/
https://ncbi.nlm.nih.gov/pubmed/18948593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804187105
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