The Endoplasmic Reticulum Grp170 Acts as a Nucleotide Exchange Factor of Hsp70 via a Mechanism Similar to That of the Cytosolic Hsp110

Grp170 and Hsp110 proteins constitute two evolutionary distinct branches of the Hsp70 family that share the ability to function as nucleotide exchange factors (NEFs) for canonical Hsp70s. Although the NEF mechanism of the cytoplasmic Hsp110s is well understood, little is known regarding the mechanis...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Andréasson, Claes, Rampelt, Heike, Fiaux, Jocelyne, Druffel-Augustin, Silke, Bukau, Bernd
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2010
الموضوعات:
Protein Structure and Folding
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852982/
https://ncbi.nlm.nih.gov/pubmed/20177057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.096735
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