Combinatorial ShcA Docking Interactions Support Diversity in Tissue Morphogenesis

Changes in protein-protein interactions may allow polypeptides to perform unexpected regulatory functions. Mammalian ShcA docking proteins have amino-terminal phosphotyrosine (pTyr) binding (PTB) and carboxyl-terminal Src homology 2 (SH2) domains, which recognize specific pTyr sites on activated rec...

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Bibliographische Detailangaben
Hauptverfasser: Hardy, W. Rod, Li, Lingying, Wang, Zhi, Sedy, Jiri, Fawcett, James, Frank, Eric, Kucera, Jan, Pawson, Tony
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575375/
https://ncbi.nlm.nih.gov/pubmed/17626887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1140114
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