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Patch–clamp coordinated spectroscopy shows P2X(2) receptor permeability dynamics require cytosolic domain rearrangements but not Panx-1 channels

ATP-gated P2X receptors display ion permeability increases within seconds of receptor activation as the channels enter the I(2) state, which is permeable to organic cations and dye molecules. The mechanisms underlying this important behavior are not completely understood. In one model, the I(2) stat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chaumont, Severine, Khakh, Baljit S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575328/
https://ncbi.nlm.nih.gov/pubmed/18689682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803008105
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