Time-Resolved Measurement of State-Specific P2X(2) Ion Channel Cytosolic Gating Motions

ATP-gated P2X(2) channels undergo permeability changes through a process that is incompletely understood. In the present study, we used fluorescence resonance energy transfer (FRET) and electrophysiology to measure cytosolic gating motions in P2X(2) channels as they enter a state with increased perm...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Fisher, James A., Girdler, Gemma, Khakh, Baljit S.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
Subjects:
Cellular/Molecular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730295/
https://ncbi.nlm.nih.gov/pubmed/15548662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3250-04.2004
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