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Hepatoma Up-Regulated Protein Is Required for Chromatin-induced Microtubule Assembly Independently of TPX2

The production of RanGTP around chromosomes is crucial for spindle microtubule assembly in mitosis. Previous work has shown that hepatoma up-regulated protein (HURP) is a Ran target, required for microtubule stabilization and spindle organization. Here we report a detailed analysis of HURP function...

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Detalhes bibliográficos
Main Authors: Casanova, Claudia M., Rybina, Sofia, Yokoyama, Hideki, Karsenti, Eric, Mattaj, Iain W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575177/
https://ncbi.nlm.nih.gov/pubmed/18799614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0624
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