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Cyclic AMP Inhibits the Proliferation of Thyroid Carcinoma Cell Lines through Regulation of CDK4 Phosphorylation

How cyclic AMP (cAMP) could positively or negatively regulate G1 phase progression in different cell types or in cancer cells versus normal differentiated counterparts has remained an intriguing question for decades. At variance with the cAMP-dependent mitogenesis of normal thyroid epithelial cells,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rocha, Ana Sofia, Paternot, Sabine, Coulonval, Katia, Dumont, Jacques E., Soares, Paula, Roger, Pierre P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575166/
https://ncbi.nlm.nih.gov/pubmed/18799615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0617
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