Cyclic AMP Inhibits the Proliferation of Thyroid Carcinoma Cell Lines through Regulation of CDK4 Phosphorylation

How cyclic AMP (cAMP) could positively or negatively regulate G1 phase progression in different cell types or in cancer cells versus normal differentiated counterparts has remained an intriguing question for decades. At variance with the cAMP-dependent mitogenesis of normal thyroid epithelial cells,...

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Hauptverfasser: Rocha, Ana Sofia, Paternot, Sabine, Coulonval, Katia, Dumont, Jacques E., Soares, Paula, Roger, Pierre P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2008
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575166/
https://ncbi.nlm.nih.gov/pubmed/18799615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0617
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