cAMP-Dependent Activation of Mammalian Target of Rapamycin (mTOR) in Thyroid Cells. Implication in Mitogenesis and Activation of CDK4

How cAMP-dependent protein kinases [protein kinase A (PKA)] transduce the mitogenic stimulus elicited by TSH in thyroid cells to late activation of cyclin D3-cyclin-dependent kinase 4 (CDK4) remains enigmatic. Here we show in PC Cl3 rat thyroid cells that TSH/cAMP, like insulin, activates the mammal...

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Bibliografiska uppgifter
Huvudupphovsmän: Blancquaert, Sara, Wang, Lifu, Paternot, Sabine, Coulonval, Katia, Dumont, Jacques E., Harris, Thurl E., Roger, Pierre P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Endocrine Society 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903905/
https://ncbi.nlm.nih.gov/pubmed/20484410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0087
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