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Cyclic AMP Inhibits the Proliferation of Thyroid Carcinoma Cell Lines through Regulation of CDK4 Phosphorylation

How cyclic AMP (cAMP) could positively or negatively regulate G1 phase progression in different cell types or in cancer cells versus normal differentiated counterparts has remained an intriguing question for decades. At variance with the cAMP-dependent mitogenesis of normal thyroid epithelial cells,...

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Detalhes bibliográficos
Main Authors: Rocha, Ana Sofia, Paternot, Sabine, Coulonval, Katia, Dumont, Jacques E., Soares, Paula, Roger, Pierre P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575166/
https://ncbi.nlm.nih.gov/pubmed/18799615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0617
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