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Activation of the Cellular DNA Damage Response in the Absence of DNA Lesions

The cellular DNA damage response (DDR) is initiated by the rapid recruitment of repair factors to the site of DNA damage to form a multiprotein repair complex. How the repair complex senses damaged DNA and then activates the DDR is not well understood. Here we demonstrate that prolonged binding of D...

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Bibliografski detalji
Glavni autori: Soutoglou, Evi, Misteli, Tom
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575099/
https://ncbi.nlm.nih.gov/pubmed/18483401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1159051
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