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The emerging role of nuclear architecture in DNA repair and genome maintenance

DNA repair and maintenance of genome stability are crucial to cellular and organismal function, and defects in these processes have been implicated in cancer and ageing. Detailed molecular, biochemical and genetic analyses have outlined the molecular framework involved in cellular DNA-repair pathway...

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Detalhes bibliográficos
Main Authors: Misteli, Tom, Soutoglou, Evi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478884/
https://ncbi.nlm.nih.gov/pubmed/19277046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2651
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