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The emerging role of nuclear architecture in DNA repair and genome maintenance

DNA repair and maintenance of genome stability are crucial to cellular and organismal function, and defects in these processes have been implicated in cancer and ageing. Detailed molecular, biochemical and genetic analyses have outlined the molecular framework involved in cellular DNA-repair pathway...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Misteli, Tom, Soutoglou, Evi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478884/
https://ncbi.nlm.nih.gov/pubmed/19277046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2651
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