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Bivalirudin decreases NO bioavailability by vascular immobilization of myeloperoxidase

Bivalirudin - a direct thrombin inhibitor - has emerged as an important alternative to heparin in patients undergoing percutaneous coronary intervention. However, it remains elusive if potentially adverse extra-coagulant properties are responsible for the fact that its favorable effects in clinical...

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Detalhes bibliográficos
Main Authors: Rudolph, Volker, Rudolph, Tanja K., Schopfer, Francisco J., Bonacci, Gustavo, Lau, Denise, Szöcs, Katalin, Klinke, Anna, Meinertz, Thomas, Freeman, Bruce A., Baldus, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575075/
https://ncbi.nlm.nih.gov/pubmed/18701766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.142414
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