Myeloperoxidase deficiency preserves vasomotor function in humans

AIMS: Observational studies have suggested a mechanistic link between the leucocyte-derived enzyme myeloperoxidase (MPO) and vasomotor function. Here, we tested whether MPO is systemically affecting vascular tone in humans. METHODS AND RESULTS: A total of 12 135 patients were screened for leucocyte...

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Detalhes bibliográficos
Main Authors: Rudolph, Tanja K., Wipper, Sabine, Reiter, Beate, Rudolph, Volker, Coym, Anja, Detter, Christian, Lau, Denise, Klinke, Anna, Friedrichs, Kai, Rau, Thomas, Pekarova, Michaela, Russ, Detlef, Knöll, Kay, Kolk, Mandy, Schroeder, Bernd, Wegscheider, Karl, Andresen, Hilke, Schwedhelm, Edzard, Boeger, Rainer, Ehmke, Heimo, Baldus, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388013/
https://ncbi.nlm.nih.gov/pubmed/21724624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehr193
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